C# Signature:

[DllImport("winmm.dll", SetLastError=true)]
static extern bool PlaySound(string pszSound,
   System.UIntPtr hmod, uint fdwSound);

/// <summary>
/// Play Sound in bytes
/// </summary>
/// <param name="pszSound">Wave File Data</param>
/// <param name="hmod"></param>
/// <param name="dwFlag">Play Flag</param>
/// <returns>succeed return true</returns>
[DllImport("winmm.dll", SetLastError=true)]
public static extern bool PlaySound(byte[] pszSound, IntPtr hmod, SoundFlags dwFlag);

VB Signature:

<DllImport("winmm.dll")> _
Shared Function PlaySound( _
   ByVal szSound As String, _
   ByVal hModule As IntPtr, _
   ByVal flags As Integer) As Integer
End Function

Notes:

    [Flags]
    public enum SoundFlags : int
    {
        SND_SYNC = 0x0000,            // play synchronously (default)
        SND_ASYNC = 0x0001,        // play asynchronously
        SND_NODEFAULT = 0x0002,        // silence (!default) if sound not found
        SND_MEMORY = 0x0004,        // pszSound points to a memory file
        SND_LOOP = 0x0008,            // loop the sound until next sndPlaySound
        SND_NOSTOP = 0x0010,        // don't stop any currently playing sound
            /// <summary>
            /// Stop Playing Wave
            /// </summary>
            SND_PURGE = 0x40,
        SND_NOWAIT = 0x00002000,        // don't wait if the driver is busy
        SND_ALIAS = 0x00010000,        // name is a registry alias
        SND_ALIAS_ID = 0x00110000,        // alias is a predefined id
        SND_FILENAME = 0x00020000,        // name is file name
        SND_RESOURCE = 0x00040004        // name is resource name or atom
    }

Tips & Tricks:

To play a sound looping both SND_LOOP and SND_ASYNC flags have to be specified. Looped sounds only stop when PlaySound is called with pszSound set to NULL.

Sample Code:

    public static void Play (string strFileName)
    {
        PlaySound (strFileName, UIntPtr.Zero, (uint)(SoundFlags.SND_FILENAME | SoundFlags.SND_ASYNC));
    }

    public static void Play (byte[] waveData)
    {
        PlaySound (waveData, IntPtr.Zero, PlayFlags.SND_ASYNC | PlayFlags.SND_MEMORY);
    }

Alternative Managed API:

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